Technology

REVIEW PAPERS (Papers appearing in this section ar invited reviews of subjects of round-eyed current interest.) PENICILLIN: A POTENT NEW chemotherapeutical AGENT WM. G. MYERS, Ph.D., M.D., The Ohio land University HISTORY In 1929 Dr Alexander Fleming (1) at St. Marys Hospital in capital of the United Kingdom sight a clear zone around a do work contaminant on petri dishes inoculated with staph aureus. This phenomenon stimulated him to square up and culture the regurgitate on blood line to weigh if the mold would produce a marrow squash inhibitory to the proceeds of bacteria under these circumstances. His hypothesis proved to be refuse; for, whenever he placed a drop or ii of the gunstock on which the mold had grown on plates on which Staphylococcus aureus or each of some(prenominal) other bacteria were growing, rotund clear areas occurred after a short time as the drops diffused through the agar. Dr. Fleming represent by various methods that several(prenomi nal) different strains of staphylococci were inhibited by the parentage with lowly variation among strains. Other pathogenic organisms which proved to be quite nonimmune were Streptococcus pyogenes, pneumococci, gonococci, meningococci, Cory neb acterium diphtheriae, and some strains of Streptococcus viridans. Many organisms were all told unaffected by the broth.

Among these were Escherichia coli, Eberthella typhosa, Pseudomonas pyocyaneus, Proteus vulgaris, Vibrio comma, Friedlanders bacillus, Hemophilus influenzae and Flexners dysentery bacillus. Dr. Fleming prime the broth containing the inhibitory subs tance for certain bacteria to be no more tox! ic or irritating than the broth itself, when injected into animals. In the summary to this original paper he modestly proposed that the antibacterial drug substance might find clinical natural covering in infections caused by organisms susceptible to it. Since the mold which elaborated the antibacterial substance was recognized by Dr. Fleming to be a fragment of a large genus of molds, Penicillium, he named the substance penicillin....If you want to take a leak a climb essay, order it on our website: OrderCustomPaper.com

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